Now showing items 1-2 of 2
GRIM-Filter: Fast seed location filtering in DNA read mapping using processing-in-memory technologies
(BioMed Central Ltd., 2018-05-09)
Background: Seed location filtering is critical in DNA read mapping, a process where billions of DNA fragments (reads) sampled from a donor are mapped onto a reference genome to identify genomic variants of the donor. ...
GateKeeper: a new hardware architecture for accelerating pre-alignment in DNA short read mapping
(Oxford Univ Press, 2017-11-01)
Motivation: High throughput DNA sequencing (HTS) technologies generate an excessive number of small DNA segments - called short reads- that cause significant computational burden. To analyze the entire genome, each of the ...