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Genetic polymorphisms of vitamin D3 metabolizing CYP24A1 and CYP2R1 enzymes in Turkish patients with ischemic stroke

Türkanoğlu Özçelik, Aysun; Öner, Tuğçe; Can Demirdöğen, Birsen; Bek, Vedat Semai; Demirkaya, Şeref; Adalı, Orhan (Taylor and Francis Ltd., 2018-05-04)

Objective: Vitamin D deficiency is known as an important risk factor in pathogenesis of atherosclerosis, which contributes to stroke development. Genetic variations including single nucleotide polymorphisms (SNPs) in enzymes ...

Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population

Bilgin, Esra; Can Demirdöğen, Birsen; Türkanoğlu Özçelik, Aysun; Demirkaya, Şeref; Adalı, Orhan (Taylor and Francis Ltd., 2019-02-01)

Objectives: Oxidative stress is a known risk factor for the pathogenesis of atherosclerosis, the main cause of ischemic stroke. Glutathione S-transferase (GST) omega-1 and omega-2, members of phase II enzymes, play a role ...