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dc.contributor.authorDemirkaya, Kadriye
dc.contributor.authorCan Demirdöğen, Birsen
dc.contributor.authorTorun, Zeynep Oncel
dc.contributor.authorErdem, Onur
dc.contributor.authorCetinkaya, Serdar
dc.contributor.authorAkay, Cemal
dc.date.accessioned2019-05-23T05:48:45Z
dc.date.available2019-05-23T05:48:45Z
dc.date.issued2016-02
dc.identifier.citationDemirkaya, K., Can Demirdöğen, B., Öncel Torun, Z., Erdem, O., Çetinkaya, S., & Akay, C. (2016). In vivo evaluation of the effects of hydraulic calcium silicate dental cements on plasma and liver aluminium levels in rats. European journal of oral sciences, 124(1), 75-81.en_US
dc.identifier.issn0909-8836
dc.identifier.othernumber of pages 7
dc.identifier.urihttps://doi.org/10.1111/eos.12238
dc.identifier.urihttp://hdl.handle.net/20.500.11851/1040
dc.description.abstractOur aim was to test whether the presence of three hydraulic calcium silicate dental cements - MTA Angelus, MTA Fillapex, and Theracal LC - in the dental extraction socket of an in vivo model, would affect the levels of aluminium (Al) in the plasma and liver. Following anesthesia, the right upper incisor of each male Wistar albino rat was extracted and polyethylene tubes filled with MTA Angelus, MTA Fillapex, or Theracal LC were inserted into the depth of the extraction socket and gingival tissue was sutured. The rats were killed 7, 30, or 60 d after the operation. Blood and liver samples were obtained from the rats before they were killed, and the levels of Al were measured by atomic absorption spectrometry. Plasma Al levels were higher in the rats in which the mineral trioxide aggregate (MTA) cements were implanted, especially MTA Angelus and MTA Fillapex, compared with control rats. In liver samples, however, the differences in Al level were not statistically significant. Our results show that Al might have been released into the circulation from the three dental cements tested, especially MTA Angelus and MTA Fillapex. Further research should be carried out on the possible biological effects of Al liberated from dental cements.en_US
dc.language.isoengen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjecttheracal lcen_US
dc.subjectmta fillapexen_US
dc.subjectmta angelusen_US
dc.subjectmineral trioxide aggregateen_US
dc.subjectendodonticsen_US
dc.titleIn vivo evaluation of the effects of hydraulic calcium silicate dental cements on plasma and liver aluminium levels in ratsen_US
dc.typearticleen_US
dc.relation.journalEuropean Journal Of Oral Sciencesen_US
dc.contributor.departmentTOBB ETU, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.contributor.departmentTOBB ETÜ, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.identifier.volume124
dc.identifier.issue1
dc.identifier.startpage75
dc.identifier.endpage81
dc.contributor.orcidhttps://orcid.org/0000-0002-1536-6123
dc.identifier.wosWOS:000367956900012
dc.identifier.scopus2-s2.0-84953835496
dc.contributor.tobbetuauthorCan Demirdöğen, Birsen
dc.identifier.PubMedIDPMID:26706154
dc.identifier.doi10.1111/eos.12238
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.relation.otherGulhane Military Medical Academy Research Project Fund [ARE-2013/39]


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