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dc.contributor.authorTan, Mehmet
dc.date.accessioned2019-07-10T14:42:46Z
dc.date.available2019-07-10T14:42:46Z
dc.date.issued2014
dc.identifier.citationTan, M. (2014, November). Drug sensitivity prediction for cancer cell lines based on pairwise kernels and miRNA profiles. In 2014 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) (pp. 156-161). IEEE.en_US
dc.identifier.isbn978-1-4799-5669-2
dc.identifier.issn2156-1125
dc.identifier.urihttps://ieeexplore.ieee.org/document/6999145
dc.identifier.urihttp://hdl.handle.net/20.500.11851/2025
dc.descriptionIEEE International Conference on Bioinformatics and Biomedicine (IEEE BIBM) (2014 : Belfast; United Kingdom)
dc.description.abstractCancer cell lines comprise an important tool to design and evaluate new drug candidates. Prediction of in vivo drug response for cancer cell lines has become attractive due to recently issued large scale drug screen databases. The data provided by these databases can be the key to model drug sensitivity for cancer cell lines. The data provided by these databases is in the form of drug cell line pairs where a natural method for prediction of drug response, therefore is pairwise support vector machines. This paper presents results on the application of pairwise kernels for drug response prediction, where the results are promising compared to some previously well-performed methods on this task. In addition, effect of exploiting microRNA profiles of cancer cell lines together with mRNA profiles is given.en_US
dc.description.sponsorshipBioBusiness,et al.,IEEE,National Science Foundation (NSF),Nsilico-Simplicity,University of Ulster
dc.language.isoengen_US
dc.publisherIEEEen_US
dc.relation.ispartofIEEE International Conference on Bioinformatics and Biomedicine-BIBM
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPharmaceutical Preparationsen_US
dc.subjectNeoplasmsen_US
dc.subjectSensitivity predictionen_US
dc.titleDrug sensitivity prediction for cancer cell lines based on pairwise kernels and miRNA profilesen_US
dc.typeconferenceObjecten_US
dc.contributor.departmentTOBB ETU, Faculty of Engineering, Department of Computer Engineeringen_US
dc.contributor.departmentTOBB ETÜ, Mühendislik Fakültesi, Bilgisayar Mühendisliği Bölümütr_TR
dc.contributor.orcidhttps://orcid.org/0000-0002-1741-0570
dc.identifier.wosWOS:000377412300181
dc.identifier.scopus2-s2.0-84922787395
dc.contributor.tobbetuauthorTan, Mehmet
dc.contributor.YOKid110845
dc.identifier.doi10.1109/BIBM.2014.6999145
dc.contributor.wosresearcherIDI-2328-2019
dc.contributor.ScopusAuthorID36984623900
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıtr_TR


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