Prevention of Candida biofilm formation over polystyrene by plasma polymerization technique
Kaleli Can, Gizem
Özgüzar, Hatice Ferda
Mirza, Hasan Cenk
Göçmen, Jülide Sedef
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Abstract This work investigates the antifungal effect of plasma polymer films produced by low-pressure RF-generated plasma system using acrylic acid, 2-hydroxyethyl methacrylate, and diethyl phosphite (DEP). Unmodified and plasma-modified polystyrene (PS) microplate wells were tested by 30 biofilm-positive Candida spp. isolated from blood samples and two control strains using a quantitative plaque assay method. Regardless of the precursors and plasma parameters, biofilm formation was inhibited for all plasma-modified microplate wells. The most significant anti-biofilm effect was observed on PS modified by DEP at 90 W plasma power with the inhibition of all Candida species' biofilm formation.
URIhttps://doi.org/10.1557/mrc.2020.79[Opens in a new window]