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dc.contributor.authorKaleli Can, Gizem
dc.contributor.authorÖzgüzar, Hatice Ferda
dc.contributor.authorKahriman, Selahattin
dc.contributor.authorTürkal, Miranda
dc.contributor.authorGöçmen, Jülide Sedef
dc.contributor.authorYurtçu, Erkan
dc.contributor.authorMutlu, Mehmet
dc.identifier.citationKaleli-Can, G., Özgüzar, H. F., Kahriman, S., Türkal, M., Göçmen, J. S., Yurtçu, E., & Mutlu, M. (2020). Improvement in antimicrobial properties of titanium by diethyl phosphite plasma-based surface modification. Materials Today Communications, 25, 101565.en_US
dc.identifier.otherarticle number 101565
dc.description.abstractTitanium (Ti) has been commonly used as a biomaterial for dental applications. However, they have struggled with the formation of polymicrobial infections leading to peri-implantitis. In this research, antimicrobial activity of titanium modified via diethyl phosphite (DEP) plasma onto Staphylococcus aureus (S. aureus) and Candida albicans (C. albicans), the two most frequently encountered pathogens in peri-implantitis, were investigated. Surface modification with DEP was achieved with plasma polymerization technique in a low-pressure/radio-frequency plasma using 75 W of plasma power and 10 min of exposure time under 0.15 mbar. Hydrophilicity, surface energy and roughness of Ti surface was increased and anionic Ti surface became amphoteric after surface modification according to physical and chemical examinations. This process significantly enhanced the antimicrobial efficiency of Ti towards S. aureus and C. albicans cells compared to control groups via contact killing. Moreover, DEP coating shown excellent compatibility with 93 % of L929 fibroblast cell viability. These findings revealed that amphoteric plasma polymer prepared from DEP offers promising solution for preventing biofilm formation on Ti.en_US
dc.publisherElsevier Ltden_US
dc.subjectPlasma polymerizationen_US
dc.subjectAmphoteric polymeren_US
dc.subjectAntimicrobial coatingen_US
dc.subjectFungicidal activityen_US
dc.subjectAntibacterial activityen_US
dc.titleImprovement in antimicrobial properties of titanium by diethyl phosphite plasma-based surface modificationen_US
dc.relation.journalMaterials Today Communicationsen_US
dc.contributor.departmentTOBB ETU, Faculty of Medicine, Department of Basic Medical Sciencesen_US
dc.contributor.departmentTOBB ETU, Faculty of Engineering, Department of Biomedical Engineeringen_US
dc.contributor.departmentTOBB ETÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümütr_TR
dc.contributor.departmentTOBB ETÜ, Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümütr_TR
dc.contributor.tobbetuauthorGöçmen, Jülide Sedef
dc.contributor.tobbetuauthorMutlu, Mehmet
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR

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