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dc.contributor.authorAbdullayeva, N.
dc.contributor.authorKumtepe, A.
dc.contributor.authorAltaf, CT
dc.contributor.authorSeçkin, H.
dc.contributor.authorSankir, Nurdan Demirci
dc.contributor.authorSankir, Mehmet
dc.date.accessioned2021-01-27T13:24:31Z
dc.date.available2021-01-27T13:24:31Z
dc.date.issued2020-10
dc.identifier.citationAbdullayeva, N., Kumtepe, A., Altaf, C. T., Seckin, H., Sankir, N. D., and Sankir, M. (2020). Dual-Ionomer-Based Device: Acetylcholine Transport and Nonenzymatic Sensing. ACS Applied Materials and Interfaces, 12(44), 50039-50051.en_US
dc.identifier.issn19448244
dc.identifier.urihttps://pubs.acs.org/doi/10.1021/acsami.0c13725
dc.identifier.urihttp://hdl.handle.net/20.500.11851/4101
dc.description.abstractThe malfunctioning in the release of acetylcholine (ACh+), leading to consequential damages in the neural system, has become an impulsion for the development of numerous progressive transport and detection gadgets. However, several challenges, such as laterality and complexity of transport devices, low precision of amperometric detection systems, and sumptuous, multistaged enzymatic quantification methods, have not yet been overcome. Herein, ionomers, because of their selective ion transporting nature, are chosen as suitable candidates for being implemented into both targeted ACh+ delivery and sensing systems. Based on these two approaches, for the very first time in the literature, the disulfonated poly(arylene ether sulfone) membrane is concurrently (i) used in the mimicry of transduction of the electrical-to-ionic signal in a neural network as “Acetylcholine Pen” (ACh+ Pen) and (ii) operated as a highly sensitive, conductivity-based ACh+ quantifier. Our dual device, being able to operate under an actual action potential of 55 mVbias, shows a strong potential of future applicability in real-time ionic delivery-and-sensing systems.en_US
dc.language.isoengen_US
dc.publisherAmerican Chemical Societyen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIonomeren_US
dc.subjectacetylcholine transporten_US
dc.subjectbiosensoren_US
dc.subjectimpedance spectroscopyen_US
dc.subjectmembraneen_US
dc.titleDual-Ionomer-Based Device: Acetylcholine Transport and Nonenzymatic Sensingen_US
dc.typearticleen_US
dc.relation.journalACS Applied Materials and Interfacesen_US
dc.contributor.departmentTOBB ETU, Faculty of Engineering, Department of Material Science & Nanotechnology Engineeringen_US
dc.contributor.departmentTOBB ETÜ, Mühendislik Fakültesi, Malzeme Bilimi ve Nanoteknoloji Mühendisliği Bölümütr_TR
dc.identifier.volume12
dc.identifier.issue44
dc.identifier.startpage50039
dc.identifier.endpage50051
dc.relation.tubitakinfo:eu-repo/grantAgreement/TÜBİTAK/MAG/217M641en_US
dc.contributor.orcidhttps://orcid.org/0000-0002-7004-1217
dc.contributor.orcidhttps://orcid.org/0000-0003-2103-0439
dc.identifier.scopus2-s2.0-85095668178
dc.contributor.tobbetuauthorSankir, Mehmet
dc.contributor.tobbetuauthorSankir, Nurdan Demirci
dc.identifier.doi10.1021 / acsami.0c13725
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıtr_TR


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