• Effects of Systemic and Local Caffeine on Vessel Diameter, Anastomosis Patency, and Intimal Hyperplasia in the Rat 

  Sakarya, Ahmet Hamdi; Uzun, Hakan; Turkkani, Ayten; Cakar, Ayse Nur; Hsieh, Yun-Huan; Ustun, Galip Gencay; Safak, Tunc (THIEME MEDICAL PUBL INC, 2019)

  Background The use of caffeine is not recommended prior to elective microsurgery due to its demonstrated negative effects on vessel anastomosis by the presumed sympathomimetic induction of vasoconstriction. In this study, ...
• A bioartificial rat heart tissue: Perfusion decellularization and characterization 

  Ozlu, Busra; Ergin, Mert; Budak, Sevcan; Tunali, Selcuk; Yildirim, Nuh; Erisken, Cevat (SAGE PUBLICATIONS LTD, 2019)

  Despite remarkable advancement in the past decades, heart-related defects are still prone to progress irreversibly and can eventually lead to heart failure. A personalized extracellular matrix-based bioartificial heart ...
• Prenatal enzymatic diagnosis of lysosomal storage diseases using cultured amniotic cells, uncultured chorionic villus samples, and fetal blood cells: Hacettepe experience 

  Unal, Canan; Ozkara, Hatice Asuman; Tanacan, Atakan; Fadiloglu, Erdem; Lay, Incilay; Topcu, Meral; Cakar, Ayse Nur; Beksac, Mehmet Sinan (WILEY, 2019)

  What's already known? Prenatal diagnosis of lysosomal storage diseases is important to avoid high morbidity and mortality. What does this study add? Enzyme analysis may be alone used safely for the prenatal diagnosis of ...
• Ex Vivo Expansion of Human Umbilical Cord Blood Hematopoietic Stem Cells with Valproic Acid or Nicotinamide is Able to Accelerate Engraftment in a NSG Mouse Transplant Model 

  Dilek, Y.; Akin, H. Y.; Turasan, E.; Karakaya, H.; Ozisik, M. S.; Fadiloglu, E.; Tanacan, A.; Yurdakul-Mesutoglu, P.; Beksac, M. (Wolters Kluwer Health Inc, 2019)

  Background: The major obstacle against wider use of cord blood (CB) hematopoietic stem cells (HSC) is low level of HSC counts causing delay in both hematopoietic and immunological recovery. In recent years, HSC expansion ...
• Do fair and just systems require compensation for the disadvantages of the natural lottery? A discussion on society’s duties on the provision of gene therapy 

  Ekmekci, P. E; Guner, M. D. (MACEDONIAN ACAD SCIENCES ARTS, 2019)

  Genetic diseases have been thought to be acquired as a result of sheer bad luck. However, recent advances in medical science have demonstrated the mechanisms of genetic disorders, which enable us to intervene with their ...
• Photobiomodulation with polychromatic light increases zone 4 survival of transverse rectus abdominis musculocutaneous flap 

  Calis, Mert; Demirtas, Tugrul Tolga; Sert, Gokhan; Irmak, Gulseren; Gumusderelioglu, Menemse; Turkkani, Ayten; Cakar, Ayse Nur; Ozgur, Figen (WILEY, 2019)

  Objective The aim of this study was to evaluate the effect of relatively novel approach of application of polychromatic light waves on flap survival of experimental musculocutaneous flap model and to investigate efficacy ...
• Inconsistencies in institutional review board decisions: A proposal to regulate the decision-making process 

  Ekmekci, P. E.; Guner, M. D. (Comenius University, 2019)

  Medical sciences and medical technologies are developing in an enormous pace. The number of multi-site and multi-cultural clinical trials is increasing in line with this development. Yet, the increase in number brought ...
• Prediction of Intramolecular Reorganization Energy Using Machine Learning 

  Atahan-Evrenk, Sule; Atalay, F. Betul (AMER CHEMICAL SOC, 2019)

  Facile charge transport is desired for many applications of organic semiconductors (OSCs). To take advantage of high-throughput screening methodologies for the discovery of novel OSCs, parameters relevant to charge transport ...
• Standardizing Decision-Making Processes in Institutional Review Boards in Accordance with International Guidelines and Turkish Regulations 

  Ekmekci, P. E.; Guner, M. D. (2018)

  All research on human subjects should go through objective and independent ethical review. However, there are huge inconsistencies in the decisions of the review boards, which lead the investigators to question the validity ...
• A method comparison for D-Dimer measurement 

  Akışın, Y. A. (Turkish Biochemical Society, 2018)

  OBJECTIVES:D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. The determination of D-dimer concentration may ...
• Evaluation of Ethical Analyses in Seven Reports from the European Network for Health Technology Assessment 

  Ekmekci, P. E.; Guner, M. D. (CAMBRIDGE UNIV PRESS, 2019)

  Objectives Ethics has been considered among the core domains of health technology assessment (HTA), but there are still disputes regarding ethical analysis. This study aimed to examine full final reports of the European ...
• Traditional Chinese Medicine from 3.000 Years Ago; History, Present and Future. 

  Ekmekci, P. E. (Turkiye Klinikleri, 2018)

  Traditional medicine is the name given to health practices that include different methods, such as plant, animal and/or mineral medicines, spiritual treatments, manual techniques and exercises, applied alone or in combination ...
• Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus 

  Gurbuz, Rumeysa Hekimoglu; Atilla, Pergin; Orgul, Gokcen; Tanacan, Atakan; Dolgun, Anil; Cakar, Ayse Nur; Beksac, Mehmet Sinan (TAYLOR & FRANCIS INC, 2019)

  Objective: To evaluate the impact of type-1 diabetes mellitus (DM) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms on impaired placentation leading to early pregnancy loss. Methods: Miscarriage materials were ...
• A Turning Point in History of Psychiatry: The Developments and Their Impact in Europe in 19 th Century 

  Ekmekci, P. E. (2018)

  19. yüzyıl psikiyatri alanında akıl hastalıklarının etiyolojisi, patogenezi ve tedavisi açısın- dan ilk gelişmelerin saptandığı; deliliğin yerine akıl hastalığı, insanlık dışı tecrit ve tespit yöntem- leri yerine ahlaki ...
• Short History of Research Ethics With Selected Cases 

  Ekmekci, Perihan Elif (Pamukkale Tıp Dergisi, 2017)

  Research ethics improved by the increase in number and variety of clinical and sociological research on human subjects. The developments in medicine and technology produced possibilities which were not present in the years ...
• Stem Cells, Definition, Types and Ethics 

  Çakar, Ayşe Nur (Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş. , 2015-05)

  Stem cells provide the development of tissues and organs during embryonic/fetal periods. After birth and in adults, they are necessary for the maintenance and repair of the tissues/organs. Under appropriate conditions, in ...
• Phacomatosis 

  Ayter, Şükriye (Ortadoğu Reklam Tanıtım Yayıncılık Turizm Eğitim İnşaat Sanayi ve Ticaret A.Ş. , 2013-10)

  The phakomatoses have often been referred to as neurocutaneous conditions because of the frequent involvement of the skin, the eyes, and the nervous system, but other tissues (e.g., bone in NF1 and kidney in TSC) are also ...
• A comparison of basilar artery diameters measured by T2WI and TOF MR angiography. 

  Celebioglu, E. C.; Aldur, M. M.; Tunalı, Selçuk; Hayran, M.; Tascioglu, A. B.; Sargon, F. M. (Springer-Verlag France, 2017-11)

  The purpose of our study is to compare basilar artery diameters (BAD) measured by T2WI to diameters measured by TOF MR angiography (MRA). By doing this, we hope to understand how compatible these two methodologies are with ...
• The Effect of Prenatal Invasive Tests on Neonatal Birthweight 

  Tanacan, A.; Aydın, E.; Çakar, Ayşe Nur; Çağan, M.; Göksuluk, D.; Beksaç, M. S. (Medical Network, 2015-12)

  OBJECTIVE: The aim of this study is to investigate the effect of prenatal invasive procedures on neonatal birth weight. STUDY DESIGN: The present study consists of three group of pregnancies; 1) Amniocentesis group (n=97), ...
• Abortion in Islamic Ethics, and How It is Perceived in Turkey: A Secular Muslim Country 

  Ekmekci, Perihan Elif (Springer, 2017-06)

  Abortion is among the most widely discussed concepts of medical ethics. Since the well-known ethical theories have emerged from Western world, the position of Islamic ethics regarding main issues of medical ethics has been ...

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