• Ribosome biogenesis mediates antitumor activity of flavopiridol in CD44(+)/CD24(-) breast cancer stem cells 

  Erol, Ayse; Acikgoz, Eda; Guven, Ummu; Duzagac, Fahriye; Türkkanı, Ayten; Colcimen, Nese; Oktem, Gulperi (Spandidos Publications, 2017-12)

  Flavopiridol is a synthetically produced flavonoid that potently inhibits the proliferation of human tumor cell lines. Flavopiridol exerts strong antitumor activity via several mechanisms, including the induction of cell ...
• Urinary tract infections and affecting factors detected in tobb university of economics and technology faculty of medicine hospital: A 5-year retrospective study 

  Yurdakul-Mesutoğlu, Pınar; Yavuzdemir, Ş.; Ardıçoğlu-Akışın, Yasemin; Kahraman, R.; Özcan, G.; Yüksel, O.; Tekmen, G.; Emri, C.; Göçmen, Jülide Sedef (AVES, 2019-12)

  Objective: The aim of this study was to retrospectively analyse the data of patients with significant bacteriuria pre-diagnosed as urinary tract infection (UTI) and to compare the results with the current literature. ...
• Hemoglobin Ve Nitrit Bağımlı Tirozin Nitrasyonu 

  Karageçili, Hasan; Kılınç, Kamer (Gumushane UniversityGümüşhane Üniversitesi, 2017)

  Nitric oxide (NO) reacts with oxyhemoglobin or oxymyoglobin resulting in the generation of nitrate and metHb or metMb. Unlike the case of nitrate, nitrite is not an innocuous end product of NO oxidation. Hemoproteins ...
• Bir Bakışta Tıbbi Mikrobiyoloji ve Enfeksiyon 

  Gillespie, Stephen; Bamford, Kathleen (Akademisyen Kitabevi, 2019-09)
• Basitleştirilmiş Klinik Anatomi 

  Goldberg, Stephen; Ouellette, Hugue (Ankara Nobel Tıp Kitabevleri, 2019-01)
• Prediction of Intramolecular Reorganization Energy Using Machine Learning 

  Atahan Evrenk, Sule; Atalay, Fatma Betül (AMER CHEMICAL SOC, 2019)

  Facile charge transport is desired for many applications of organic semiconductors (OSCs). To take advantage of high-throughput screening methodologies for the discovery of novel OSCs, parameters relevant to charge transport ...
• Ex Vivo Expansion of Human Umbilical Cord Blood Hematopoietic Stem Cells with Valproic Acid or Nicotinamide is Able to Accelerate Engraftment in a NSG Mouse Transplant Model 

  Dilek, Y.; Akin, H. Y.; Turasan, E.; Karakaya, H.; Ozisik, M. S.; Fadiloglu, E.; Tanacan, A.; Yurdakul-Mesutoglu, P.; Beksac, M. (Wolters Kluwer Health Inc, 2019)

  Background: The major obstacle against wider use of cord blood (CB) hematopoietic stem cells (HSC) is low level of HSC counts causing delay in both hematopoietic and immunological recovery. In recent years, HSC expansion ...
• Effects of Systemic and Local Caffeine on Vessel Diameter, Anastomosis Patency, and Intimal Hyperplasia in the Rat 

  Sakarya, Ahmet Hamdi; Uzun, Hakan; Turkkani, Ayten; Cakar, Ayse Nur; Hsieh, Yun-Huan; Ustun, Galip Gencay; Safak, Tunc (THIEME MEDICAL PUBL INC, 2019)

  Background The use of caffeine is not recommended prior to elective microsurgery due to its demonstrated negative effects on vessel anastomosis by the presumed sympathomimetic induction of vasoconstriction. In this study, ...
• Photobiomodulation with polychromatic light increases zone 4 survival of transverse rectus abdominis musculocutaneous flap 

  Calis, Mert; Demirtas, Tugrul Tolga; Sert, Gokhan; Irmak, Gulseren; Gumusderelioglu, Menemse; Turkkani, Ayten; Cakar, Ayse Nur; Ozgur, Figen (WILEY, 2019)

  Objective The aim of this study was to evaluate the effect of relatively novel approach of application of polychromatic light waves on flap survival of experimental musculocutaneous flap model and to investigate efficacy ...
• A bioartificial rat heart tissue: Perfusion decellularization and characterization 

  Ozlu, Busra; Ergin, Mert; Budak, Sevcan; Tunalı, Selçuk; Yildirim, Nuh; Erisken, Cevat (SAGE PUBLICATIONS LTD, 2019)

  Despite remarkable advancement in the past decades, heart-related defects are still prone to progress irreversibly and can eventually lead to heart failure. A personalized extracellular matrix-based bioartificial heart ...
• Prenatal enzymatic diagnosis of lysosomal storage diseases using cultured amniotic cells, uncultured chorionic villus samples, and fetal blood cells: Hacettepe experience 

  Unal, Canan; Ozkara, Hatice Asuman; Tanacan, Atakan; Fadiloglu, Erdem; Lay, Incilay; Topcu, Meral; Cakar, Ayse Nur; Beksac, Mehmet Sinan (WILEY, 2019)

  What's already known? Prenatal diagnosis of lysosomal storage diseases is important to avoid high morbidity and mortality. What does this study add? Enzyme analysis may be alone used safely for the prenatal diagnosis of ...
• Inconsistencies in institutional review board decisions: A proposal to regulate the decision-making process 

  Ekmekci, Perihan Elif; Güner, Müberra Devrim (Comenius University, 2019)

  Medical sciences and medical technologies are developing in an enormous pace. The number of multi-site and multi-cultural clinical trials is increasing in line with this development. Yet, the increase in number brought ...
• Do fair and just systems require compensation for the disadvantages of the natural lottery? A discussion on society’s duties on the provision of gene therapy 

  Ekmekci, Perihan Elif; Güner, Müberra Devrim (MACEDONIAN ACAD SCIENCES ARTS, 2019)

  Genetic diseases have been thought to be acquired as a result of sheer bad luck. However, recent advances in medical science have demonstrated the mechanisms of genetic disorders, which enable us to intervene with their ...
• A method comparison for D-Dimer measurement 

  Akışın, Y. A. (Turkish Biochemical Society, 2018)

  OBJECTIVES:D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. The determination of D-dimer concentration may ...
• Evaluation of Ethical Analyses in Seven Reports from the European Network for Health Technology Assessment 

  Ekmekci, Perihan Elif; Güner, Müberra Devrim (Cambridge University Press, 2019)

  Objectives Ethics has been considered among the core domains of health technology assessment (HTA), but there are still disputes regarding ethical analysis. This study aimed to examine full final reports of the European ...
• Standardizing Decision-Making Processes in Institutional Review Boards in Accordance with International Guidelines and Turkish Regulations 

  Ekmekci, Perihan Elif; Güner, Müberra Devrim (2018)

  All research on human subjects should go through objective and independent ethical review. However, there are huge inconsistencies in the decisions of the review boards, which lead the investigators to question the ...
• Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus 

  Gurbuz, Rumeysa Hekimoglu; Atilla, Pergin; Orgul, Gokcen; Tanacan, Atakan; Dolgun, Anil; Cakar, Ayse Nur; Beksac, Mehmet Sinan (TAYLOR & FRANCIS INC, 2019)

  Objective: To evaluate the impact of type-1 diabetes mellitus (DM) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms on impaired placentation leading to early pregnancy loss. Methods: Miscarriage materials were ...
• 3.000 Yıl Öncesinden Günümüze Geleneksel Çin Tıbbı; Tarihi, Bugünü ve Geleceği 

  Ekmekci, Perihan Elif (Turkiye Klinikleri, 2018)

  Traditional medicine is the name given to health practices that include different methods, such as plant, animal and/or mineral medicines, spiritual treatments, manual techniques and exercises, applied alone or in combination ...
• Psikiyatri Tarihinde Bir Dönüm Noktası: 19. Yüzyılda Avrupa’daki Gelişmeler ve Etkileri 

  Ekmekci, Perihan Elif (2018)

  19. yüzyıl psikiyatri alanında akıl hastalıklarının etiyolojisi, patogenezi ve tedavisi açısın- dan ilk gelişmelerin saptandığı; deliliğin yerine akıl hastalığı, insanlık dışı tecrit ve tespit yöntem- leri yerine ahlaki ...
• Flow Cytometric Aldehyde Dehydrogenase (ALDH) Assay Enables a Fast and Accurate Human Umblical Cord Blood Hematopoietic Stem Cell Assessment. 

  Gencer, Emine Begüm; Yurdakul, Pınar; Dalva, Klara; Beksaç, Meral (Galenos Yayıncılık, 2017-11)

  OBJECTIVE: Colony-forming units of granulocytes/macrophages (CFU-GM) analysis is the most widely used method to determine the hematopoietic stem cell (HSC) content of human umbilical cord blood (CB) for prediction of ...

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