Temel Tıp Bilimleri Bölümü / Department of Basic Medical Sciences
Recent Submissions
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Beyond A Game: Peer Education To Separate Football And Violence
(2017-09)Football, one of the sports with roots in history, has been associated with violence and tragedy in various countries. Several studies have tried to understand the nature and structure of hooliganism and its common ... -
Ribosome biogenesis mediates antitumor activity of flavopiridol in CD44(+)/CD24(-) breast cancer stem cells
(Spandidos Publications, 2017-12)Flavopiridol is a synthetically produced flavonoid that potently inhibits the proliferation of human tumor cell lines. Flavopiridol exerts strong antitumor activity via several mechanisms, including the induction of cell ... -
Urinary tract infections and affecting factors detected in tobb university of economics and technology faculty of medicine hospital: A 5-year retrospective study
(AVES, 2019-12)Objective: The aim of this study was to retrospectively analyse the data of patients with significant bacteriuria pre-diagnosed as urinary tract infection (UTI) and to compare the results with the current literature. ... -
Hemoglobin Ve Nitrit Bağımlı Tirozin Nitrasyonu
(Gumushane UniversityGümüşhane Üniversitesi, 2017)Nitric oxide (NO) reacts with oxyhemoglobin or oxymyoglobin resulting in the generation of nitrate and metHb or metMb. Unlike the case of nitrate, nitrite is not an innocuous end product of NO oxidation. Hemoproteins ... -
Bir Bakışta Tıbbi Mikrobiyoloji ve Enfeksiyon
(Akademisyen Kitabevi, 2019-09) -
Basitleştirilmiş Klinik Anatomi
(Ankara Nobel Tıp Kitabevleri, 2019-01) -
A bioartificial rat heart tissue: Perfusion decellularization and characterization
(SAGE PUBLICATIONS LTD, 2019)Despite remarkable advancement in the past decades, heart-related defects are still prone to progress irreversibly and can eventually lead to heart failure. A personalized extracellular matrix-based bioartificial heart ... -
Prenatal enzymatic diagnosis of lysosomal storage diseases using cultured amniotic cells, uncultured chorionic villus samples, and fetal blood cells: Hacettepe experience
(WILEY, 2019)What's already known? Prenatal diagnosis of lysosomal storage diseases is important to avoid high morbidity and mortality. What does this study add? Enzyme analysis may be alone used safely for the prenatal diagnosis of ... -
Inconsistencies in institutional review board decisions: A proposal to regulate the decision-making process
(Comenius University, 2019)Medical sciences and medical technologies are developing in an enormous pace. The number of multi-site and multi-cultural clinical trials is increasing in line with this development. Yet, the increase in number brought ... -
Do fair and just systems require compensation for the disadvantages of the natural lottery? A discussion on society’s duties on the provision of gene therapy
(MACEDONIAN ACAD SCIENCES ARTS, 2019)Genetic diseases have been thought to be acquired as a result of sheer bad luck. However, recent advances in medical science have demonstrated the mechanisms of genetic disorders, which enable us to intervene with their ... -
Photobiomodulation with polychromatic light increases zone 4 survival of transverse rectus abdominis musculocutaneous flap
(WILEY, 2019)Objective The aim of this study was to evaluate the effect of relatively novel approach of application of polychromatic light waves on flap survival of experimental musculocutaneous flap model and to investigate efficacy ... -
Effects of Systemic and Local Caffeine on Vessel Diameter, Anastomosis Patency, and Intimal Hyperplasia in the Rat
(THIEME MEDICAL PUBL INC, 2019)Background The use of caffeine is not recommended prior to elective microsurgery due to its demonstrated negative effects on vessel anastomosis by the presumed sympathomimetic induction of vasoconstriction. In this study, ... -
Prediction of Intramolecular Reorganization Energy Using Machine Learning
(AMER CHEMICAL SOC, 2019)Facile charge transport is desired for many applications of organic semiconductors (OSCs). To take advantage of high-throughput screening methodologies for the discovery of novel OSCs, parameters relevant to charge transport ... -
Ex Vivo Expansion of Human Umbilical Cord Blood Hematopoietic Stem Cells with Valproic Acid or Nicotinamide is Able to Accelerate Engraftment in a NSG Mouse Transplant Model
(Wolters Kluwer Health Inc, 2019)Background: The major obstacle against wider use of cord blood (CB) hematopoietic stem cells (HSC) is low level of HSC counts causing delay in both hematopoietic and immunological recovery. In recent years, HSC expansion ... -
3.000 Yıl Öncesinden Günümüze Geleneksel Çin Tıbbı; Tarihi, Bugünü ve Geleceği
(Turkiye Klinikleri, 2018)Traditional medicine is the name given to health practices that include different methods, such as plant, animal and/or mineral medicines, spiritual treatments, manual techniques and exercises, applied alone or in combination ... -
Impaired Placentation and Early Pregnancy Loss in Patients with MTHFR Polymorphisms and Type-1 Diabetes Mellitus
(TAYLOR & FRANCIS INC, 2019)Objective: To evaluate the impact of type-1 diabetes mellitus (DM) and methylenetetrahydrofolate reductase (MTHFR) polymorphisms on impaired placentation leading to early pregnancy loss. Methods: Miscarriage materials were ... -
A method comparison for D-Dimer measurement
(Turkish Biochemical Society, 2018)OBJECTIVES:D-dimer is a fibrin degradation product, a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. The determination of D-dimer concentration may ... -
Evaluation of Ethical Analyses in Seven Reports from the European Network for Health Technology Assessment
(Cambridge University Press, 2019)Objectives Ethics has been considered among the core domains of health technology assessment (HTA), but there are still disputes regarding ethical analysis. This study aimed to examine full final reports of the European ... -
Psikiyatri Tarihinde Bir Dönüm Noktası: 19. Yüzyılda Avrupa’daki Gelişmeler ve Etkileri
(2018)19. yüzyıl psikiyatri alanında akıl hastalıklarının etiyolojisi, patogenezi ve tedavisi açısın- dan ilk gelişmelerin saptandığı; deliliğin yerine akıl hastalığı, insanlık dışı tecrit ve tespit yöntem- leri yerine ahlaki ... -
Standardizing Decision-Making Processes in Institutional Review Boards in Accordance with International Guidelines and Turkish Regulations
(2018)All research on human subjects should go through objective and independent ethical review. However, there are huge inconsistencies in the decisions of the review boards, which lead the investigators to question the ...
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