Browsing Temel Tıp Bilimleri Bölümü / Department of Basic Medical Sciences by Submit Date
Now showing items 1-20 of 90
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Morphology of cranial sutures and radiologic evaluation of the variations of intersutural bones
(Via Medica, 2018-12-04)Background: As far as our literature searches showed us, morphological characteristics of cranium such as sutures, sutural bones and fontanelles had been examined in the skulls in the museums and dry specimens until now. ... -
Arteriography and Histopathology of Vascular Beds in Traumatically Amputated Fingers
(World Scientific, 2018-06-01)BACKGROUND: The success of replantation following traumatic amputation is determined by the quality of the vascular anastomoses. The purpose of this study was to assess the vascularity of injured arteries from traumatically ... -
New Entity of Skull Lesions due to Birth Trauma: Kanat (Wing) Fractures
(Turkish Neurosurgical Society, 2018-02-26)AIM: To discuss a special type of skull lesion detected after delivery. We reviewed our experience on scalp swelling in term neonates to further investigate the relationship between cranial injuries and labor process. MATERIAL ... -
Turkish medical students' perspectives on pediatric euthanasia
(Medicine and Law, 2018-09-01)Background The legalization and paradigmatic cases,. such as Baby Doe, have initiated a debate on pediatric euthanasia. This paper examines the historic background, the current extent of implementation, and the main ethical ... -
Heightened CXCR4 and CXCL12 expression in NF1-associated neurofibromas
(Springer Berlin Heidelberg, 2018-05-01)Neurofibromatosis type 1 (NF1) is the most common neurogenetic disorder worldwide, and its clinical presentations are highly variable. NF1 is caused by mutations in the NF1 gene, and 50% of NF1 cases are sporadic, which ... -
Ethical and legal problems arising from off-label use of medical devices and some solution recommendations
(Turkish Society of Cardiology, 2018-06-01)Tıbbi cihazların endikasyon dışı (off-label) kullanımı giderek yaygınlaşmaktadır. İlaçların endikasyon dışı kullanımının yasal ve etik açıdan kurallara bağlanmış olmasına rağmen benzer düzenlemeler tıbbi cihazlar alanında ... -
Predicting mortality and morbidity of geriatric femoral fractures using a modified frailty index and perioperative features: A prospective, multicentre and observational study
(Geriatrics Society, 2018)Femoral fracture is associated with high geriatric mortality. Frailty is the increased vulnerability to stressors resulting from aging-associated decreases in physiological reserve. We aimed to predict 30-365-day postoperative ... -
Automated washing of long-term cryopreserved peripheral blood stem cells promotes cell viability and preserves CD34+ cell numbers
(Nature Publishing Group, 2018-09-01)Peripheral blood stem cell (PBSC) transplantation has become an established treatment option for a range of malignant and inherited diseases. PBSCs are usually cryopreserved in the presence of dimethyl sulfoxide (DMSO) and ... -
The effect of parental age on NF1 patients in Turkey
(Springer Verlag, 2018-07-01)Neurofibromatosis type 1 (NF1) is the most common neurogenetic disorder worldwide, and its clinical presentations are highly variable. NF1 is caused by mutations in the NF1 gene, and 50% of NF1 cases are sporadic, which ... -
Possible modifier genes in the variation of neurofibromatosis type 1 clinical phenotypes
(Taylor and Francis Ltd, 2018-04-03)Neurofibromatosis type 1 (NF1) is the most common neurogenetic disorder worldwide, caused by mutations in the (NF1) gene. Although NF1 is a single-gene disorder with autosomal-dominant inheritance, its clinical expression ... -
Clinical findings and mutation analysis of NF1 patients in Turkey
(Elsevier B.V., 2018-02)Neurofibromatosis type 1 (NF1) is an autosomal dominant disease that is caused by mutations of the NF1 gene. NF1 is clinically characterized by neurofibromas, pigmentation anomalies, and an increased risk of malignant ... -
Asymptomatic hemochromatosis case with HFE c.1007−47G>A, c.340+4T>C heterozygous mutations and alpha globin −3.7 kb deletion
(Egyptian Society of Human Genetics, 2018-10-01)Hereditary hemochromatosis is a disease associated with iron deposition which is caused by the mutations in “hereditary Fe (iron)” (HFE) gene. Case: The 16-year-old male patient was diagnosed with hereditary hemochromatosis ... -
A quantitative structure-property study of reorganization energy for known p-type organic semiconductors
(Royal Society of Chemistry, 2018)Intramolecular reorganization energy (RE), which quantifies the electron-phonon coupling strength, is an important charge transport parameter for the theoretical characterization of molecular organic semiconductors (OSCs). ... -
Computational investigation of intramolecular reorganization energy in diketopyrrolopyrrole (DPP) derivatives
(TÜBİTAK, 2018)Intramolecular reorganization energy (RE) of molecules derived from the diketopyrrolopyrrole (DPP) unit has been studied using B3LYP/6-31G(d,p) theory. It was found that the replacement of the oxygen atoms with sulfur in ... -
Predictive Value of CC16 For Respiratory Prognosis in Occupational Gas Exposure
(Wiley, 2018-12)Aim: Even after the cessation of exposure to chemicals, occupational respiratory disease’s symptoms may not improve. Therefore, researches for predictive biomarkers are necessary. CC16 is a respiratory epithelial permeability ... -
The Effects of Stress and Serotonin System on TH Cell Activity
(Wiley, 2018-12)Aim: Stress, has varying effects on the immune system. Serotonin has important effects on both the stress response and the immune system. The aim of this study was to investigate the role of serotonin in the effects of ... -
Factors influencing the success of cord blood collection: A tertiary perinatal medicine center’s experience
(Turkiye Klinikleri Journal of Medical Sciences, 2018)This study aimed to evaluate the effects of certain maternal, fetal, and umbilical cord blood unit factors on storage and/or discard incidence of collected cord blood units from perinatal medicine patients. Materials and ... -
Differential expression of leukemia inhibitory factor and insulin like growth factor-1 between normal pregnancies, partial hydatidiform moles and complete hydatidiform moles
(W.B. Saunders Ltd., 2018-09)Leukemia inhibitory factor (LIF) and insulin like growth factor-1 (IGF-1) are two of the most important growth factors mediating trophoblast actions. We hypothesized that the localization and expression patterns of LIF and ... -
Gestational outcomes of pregnant women who have had invasive prenatal testing for the prenatal diagnosis of spinal muscular atrophy
(South African Medical Association, 2018)Spinal muscular atrophy (SMA) is a neurodegenerative disease which is characterised by progressive degeneration of motor neurons in the anterior horns of the spinal cord. It is a mainly chromosome 5-linked genetic disorder, ... -
Kan ve El Kültüründen İzole Edilen Koagülaz-Negatif Stafilokok İzolatlarının Biyofilm Oluşumunun Plazma Polimerizasyon Tekniği ile Kaplanmış Mikroplaklarda İncelenmesi: Deneysel Model
(Bilimsel Tip Yayinevi, 2017)Introduction: Coagulase-negative staphylococci (CNS) can protect themselves from the effects of antibiotics by producing biofilms through breeding on biomaterials, medical equipment and devices. It is possible to influence ...
